Directorate of Sericulture(DOS), under the Administrative control of Handloom Textiles & Sericulture Department, Government of Assam was established in the year of 1958 with a different nomenclature as Directorate of Weaving & Sericulture, Assam till July 1983. In the month of July,1983 this Directorate was separated as the Directorate of Sericulture, Assam bifurcating the Weaving as a new Directorate known as Directorate of Handloom & Textiles, Assam.

Since separation of the Directorate of Sericulture, it has been performing as a nodal Department for all activities relating to Silk & Silk Production in the State. The Headquarter of the Directorate of Sericulture, Assam is located at Khanapara just a 5 KM distance from the Capital of Assam, Dispur. This Directorate is headed by a Senior State Government Officer borne from the Assam Civil Service Senior Grade. To control the entire Sericulture mechanism in the State, the Government of Assam has created 4 Nos. of Additional Director Offices at BTC Kokrajhar, Diphu & DimaHasao; 1 Research Institute at Dhakuakhana, Lakhimpur, 2 Technological Information Centre at Gogamukh, Dhemaji&Jonai; 29 Nos. of District Offices; 28 Nos. of Sub-Divisional Offices, 384 Nos. of Farms/ Centres/Reeling & Spinning units 3 Nos. of Cocoon Bank;3 Projects, etc. Moreover a Sericulture Training Institute has been set up at Titabor under Jorhat District to impart training as Sericulture as a purely technical agro-based activity.